The Big Sip

Image: people.com
The take: When a president's pregnancy advice can vaporise $2 billion in market value, we've entered a new era where political opinion trades harder than medical consensus.
What happened: On 22 Sep 2025, Donald Trump told pregnant women to avoid Tylenol, while HHS (the U.S. Department of Health and Human Services) said the FDA (drug approvals/labels) would start a safety-label change on acetaminophen (paracetamol).
Why it matters: A single podium moment hit Kenvue shares and risked confusing prenatal care, where acetaminophen remains standard guidance from ACOG (American College of Obstetricians and Gynecologists).
What to watch: FDA’s label process and exact wording. Any ACOG update, further stock volatility, litigation chatter, and state-level advisories over the next fortnight.
Reciepts
• [Primary] FDA: label change process for acetaminophen announced on 22 Sep 2025. U.S. Food and Drug Administration
• [Report] ACOG: acetaminophen remains appropriate in pregnancy; no causal autism link. ACOG
• [Analysis] Nature: experts say strong evidence is lacking for Trump’s claim. Nature
• [Analysis] Reuters/Morningstar: Kenvue hit a record low, then partial recovery. Morningstar+1
Markets don’t read medical studies. They price the chaos. And right now, one man's medical hot take is questioning a decade of clinical trials.
Here’s The Brew

Power plays don't need peer review when you've got 90 million followers.
Within hours of Trump's Monday warning, Kenvue shed $2.1 billion as investors priced in lawsuit fears and brand damage.
The mechanism: political certainty beats scientific nuance every time in the attention economy.
Big Pharma wants stable guidance. Pregnant women want clear answers.
Trump wants the headline.
The FDA rushed to announce "forthcoming labels" without the data to back them.
Expect the wording to decide both clinic behaviour and Kenvue’s next chart.
Welcome to Medicine by Megaphone, where correlation is mistaken for causation if you say it loud enough.
Two Sides, One Mug ☕

Pro: Precautionary principle says minimise all medication during pregnancy when alternatives exist.
Con: Decades of safety data outweigh unproven correlations that could leave women suffering needlessly.
Our read: The danger isn't in the pill. It's in replacing medical consensus with political theatre while real people make health decisions based on tweets and headlines.
Receipt of the Day
FDA Adverse Event Database 2024 — Shows 47 autism-related reports among 150 million annual acetaminophen users. That's 0.00003%.
Spit Take
“Over 50% of pregnant women use acetaminophen.” — Mount Sinai. Mount Sinai Health System
Coffee Break Links ×3
• ACOG explainer — why acetaminophen still sits in prenatal toolkits. [Report] ACOG
• Reuters explainer — what studies actually say about autism risk. [Analysis] Reuters
• Nature Q&A — separating correlation noise from causal claims. [Analysis] Nature
Join your team of caffeinated skeptics.
One take, one counter, one receipt.
Six minutes.

Mugshot Poll 📊
What's your pregnancy medical advisor of choice?
Save Money, Buy Coffee
As an expat living in Vietnam for over 13 years, I’m always missing my favourite TV programmes from back home.
Whether it’s the latest Match of the Day on iPlayer or a comedy series on the UK’s Netflix, I have to use a VPN to access my British TV hit.
After being a customer for over 3 years, SurfShark is the only VPN I trust. It’s reliable, safe, and works anywhere.
Get 3 months FREE with my link: https://surfshark.club/friend/WMz5QGv9
Send It: If you enjoyed today’s episode of Curse and Coffee, share it with your fellow skeptics. Here’s the link: https://curse-and-coffee.beehiiv.com/
Be sure to get your daily curse and coffee fix by hitting that subscribe button.
Before we wrap up today…
Does crypto/Web3 intrigue you?
Is worrying about losing money or getting scammed stopping you from investing?
This course is for you!
Click to share (2 referrals get you free access to your very own crypto mastery email course).
Everything you need to unlock crypto in 5 days (for beginners).
For the love of coffee, see you tomorrow!


